The Technology that
Changed ADHD Treatment

We’ve invested over 10 years of research in ADHD to develop the core technology behind EndeavorOTC

  • 8 Clinical Studies
  • 6 Peer-reviewed Publications
  • 1,000+ Research Participants*
  • *Research participants include children, adolescents, and adults

Technology researched through collaborations between world-renowned cognitive neuroscientists and clinical researchers from leading institutions such as Duke University School of Medicine and The University of California, San Francisco.

Treatment Technology Built on Efficacy and Quality

  • Adult ADHD Clinical Trial

    After a 6-week treatment period:

    • 37% no longer exhibited an attention deficit1
    • 33% had clinically meaningful improvements in ADHD symptoms2
    • 61% reported clinically meaningful improvements in productivity3
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    • 1TOVA-ACS > 0
    • 2≥ 30% improvement on the clinician-related ADHD -Rating Scale
    • 3≥ 8-point improvement on Adult ADHD Quality of Life-Life Productivity Scale

  • Adolescent ADHD Clinical Trial

    After a 4-week treatment period:

    • 61% showed clinically meaningful improvements in attention1
    • 27% had clinically meaningful improvements in ADHD symptoms2
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    • 1≥ 1.4 point improvement on TOVA-ACS
    • 2≥ 30% improvement on the clinician-related ADHD-Rating Scale

  • Pediatric ADHD Clinical Trial

    After 4 weeks of treatment, a significantly greater proportion of the AKL-T01 treatment group (47%) showed clinically meaningful improvements in attention relative to those receiving an active digital control (p=.006)1

    Read the Trial
    • 1≥ 1.4 point improvement on TOVA-ACS

“We believe digital therapeutics should be validated by rigorous clinical research. Demonstrating effectiveness and safety of a treatment is required of any pharmaceutical and we have made it a point to set a similar standard with our Endeavor products.”

Dr. Scott Kollins, Chief Medical Officer, Akili Interactive

Clinically Proven to Improve Focus and Attention in Adults with ADHD

What We Found

In our recent clinical trial, EndeavorOTC significantly improved focus, attention, and overall quality of life in adults struggling with ADHD symptoms.

  • 1As measured by TOCA-ACS change ≥ 1.4 points
  • 2 As measured by > 0 change on the AAQoL

Participants saw an 85% improvement in their ability to focus

Baseline: -8.8 Mean TOVA-ACS. After EndeavorOTC: -2.1 Mean TOVA-ACS.
Higher (or less negative) TOVA-ACS scores indicate better attentional functioning

EndeavorOTC Improves Quality of Life

Adults in our clinical trial saw quality of life improvements across a range of important areas1, including:

Increased Productivity: 78%. Better able to get things done on time: 52%. Pay better attention when interacting with others: 50%. Better able to get started with tasks they don't find interesting: 50%. Better keep the house/apartment clean or uncluttered: 48%. Better remember important things: 46%.
  • 1Based on >0 improvement for total score (Increased productivity) and individual items of the AAQoL (remaining items listed in chart).

View All Our Studies